Introduction kleine-levin syndrome (kls) is a rare disease characterized by recurrent episodes of hypersomnia and, to various degrees, behavioural or cognitive disturbances, compulsive eating behaviour and hypersexuality (american academy of sleep medicine, 2005. This review is an update of a previously published review in the cochrane database of systematic reviews (issue 2, 2009) on 'pharmacological treatment for kleine-levin syndrome' kleine-levin syndrome (kls) is a rare disorder that mainly affects adolescent men. Kleine-levin syndrome (kls) is characterized by recurrent episodes of hypersomnia and other symptoms and it is a really challenging for the physician, since its causes are not yet clear, and available treatment options are not having adequate support. Case reports in neurological medicine is a peer-reviewed, open access journal that publishes case reports and case series focusing on diseases of the nervous system, as well as abnormal neurological function. The case highlights the need for psychiatrists to be aware of kleine-levin syndrome and the treatment options available once diagnosed this case also illustrates the efficacy of lithium in preventing relapses in patients with kleine-levin syndrome.
Kleine-levin syndrome (kls) is a rare disorder with an estimated prevalence of one to five cases per million population patients with primary kls can be found worldwide, with a higher prevalence among ashkenazi jews. Doi: 104103/0253-7176162931 kleine-levin syndrome (kls) is characterized by recurrent episodes of hypersomnia and other symptoms and it is a really challenging for the physician, since its causes are not yet clear, and available treatment options are not having adequate support. Kleine-levin syndrome (kls) is a chronic sleep disorder and is one of the central disorders of hypersomnolence (cdhs)this term refers to conditions that cause excessive daytime sleepiness, meaning that patients have trouble staying awake during the day (1. Kleine-levin syndrome (kls) is a rare (approximately two cases per million individuals) neuropsychiatric disorder of unknown origin, which primarily affects adolescents 1 it is characterized by recurrent episodes of hypersomnia, confusion, derealization, apathy, and decreased mood in addition, one-third to two-thirds of patients exhibit.
Introduction kleine-levin syndrome is an extremely rare neurological entity characterized by recurrent episodes of hypersomnia which are sometimes associated with compulsive hyperphagia and behavioral changes. Kleine-levin syndrome is a rare sleep disorder that primarily affects adolescent males, usually around the age of 16 years however, there have been cases involving females and older men. Kleine-levin syndrome is an unusual sleep disorder occurring predominantly, but not exclusively, in late adolescent males a case is described which illustrates some of the difficulties in diagnosis and management. Arnulf i, zeitzer jm, file j: kleine-levin further episodes (relapses) when levin syndrome can resemble syndrome: a systematic review of 186 compared with medical abstention psychiatric conditions the case cases in the literature. Of kleine-levin syndrome was confirmed by polysomnogram, recording normal sleep architecture between attacks (hajj te, nasreddine w, korri h, atweh s, beydoun a.
Kleine-levin syndrome (kls) also called sleeping beauty syndrome, is a rare sleep disorder with onset in early adolescence common symptoms are episodes of hypersomnolence, behavioral and cognitive disturbances (including specific feelings of. Kleine-levin syndrome (kls) is a rare disorder characterised by hypersomnia, hyperphagia and behavioural disturbances it typically occurs in adolescent men and may mimic a variety of neuropsychiatric conditions. Kleine-levin syndrome (kls) is a rare, remittent-relapsing disease mostly affecting adolescents this syndrome is characterized by episodes of major hypersomnia of one to several weeks, plus cognitive, behavioral, and psychiatric disturbances.
Google scholar see all references around 60% of the cases have one precipitating factors, the most frequent of which is a trivial flu-like symptom or nonspecific fever 2 x 2 arnulf, i kleine-levin syndrome: a systematic review of 186 cases in the literature. Kleine-levin syndrome is a recurrent hypersomnia characterized by episodes of hypersomnia separated by intervening periods of normal behavior in addition to hypersomnia, at least one of the following symptoms must be present: cognitive or mood disturbances, hyperphagia with compulsive eating. Kleine-levin syndrome (kls) is considered an exceptionally rare, recurrent condition characterised by hypersomnia, hyperphagia and behavioural disturbances including hypersexuality, depression, irritability and derealisation[1,2] it occurs typically in adolescent men, who are often misdiagnosed.
The kleine-levin syndrome is a differential diagnosis for patients with diurnal excessive sleepiness and a suspicion of narcolepsy it is characterized by paroxysmal attacks of diurnal excessive sleepiness, associated with one or more symptoms of hyperphagia, hypersexuality, coprolalia and copropraxia. Kleine-levin syndrome (kls) is a rare disorder which mainly affects adolescent boys and characterized by recurrent episodes of hypersomnia, and sometime along with hyperphagia, behavioral and cognitive disturbances, and hypersexuality. Vol 37 issue 3 jul-sep 2015 successful use of valproate in kleine-levin syndrome: a case report and review of cases valproate in kleine-levin syndrome: a case report and review of cases. Kleine-levin syndrome is a rare disease of uncertain etiology characterized by recurrent episodes of hypersomnia and to various degrees, behavioral or cognitive disturbances, compulsive eating behavior and hyper sexuality.
Clinical observations kleine-levin syndrome: a case report and review of literature sourav das mda, ravi gupta md phda,, mohan dhyani mda, shailendra raghuvanshi mdb adepartment of psychiatry and sleep clinic, himalayan institute of medical sciences, doiwala, dehradun, india. Case report sleep-related psychosis lukas frase,1 barbara sixt,2 christoph nissen1 1department of psychiatry and psychotherapy, university medical center freiburg, freiburg, germany. Introduction: kleine-levin syndrome is a rare neurological disorder (1-2 cases per million inhabitants) primarily affecting young subjects it is characterized by relapsing-remitting episodes of hypersomnia in association with cognitive and behavioral disturbances.